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NFL Week 17 Monday Night Football winners picks: Lions vs 49ers predictions

December 30, 2024 by The Phinsider

Atlanta Falcons v. Minnesota Vikings
Photo by Todd Rosenberg/Getty Images

Our Week 17 predictions for the Monday Night Football game between the Detroit Lions and San Francisco 49ers.

Week 17 has been full of games with playoff implications. The Monday Night Football conclusion to the week, featuring the Detroit Lions visiting the San Francisco 49ers, is one of the few games that really does not impact the postseason. The NFC playoff picture is fairly well set, with the Lions and Minnesota Vikings set to battle in the Sunday Night Football season finale next week to decide who wins the NFC North and claims the top seed in the conference. Tonight’s game does not change anything about next week’s game.

The 49ers have been eliminated from the playoffs and are only playing for pride this weekend. It has been a disappointing season for San Francisco, who are 6-9 and in last place in the NFC West. How will a team with nothing to play for look on a primetime game?

We will find out when the Lions and 49ers kickoff at 8:15 p.m. Eastern. There is just one game tonight, with both ABC and ESPN handling the broadcast.

What are the latest FanDuel sportsbook odds?

The line for tonight is probably closer than would be expected between a 13-2 Lions team and a 6-9 49ers team. The spread, as of 5 p.m. Eastern on Monday, had Detroit favored by just 3.5 points. The Lions are -200 on the moneyline, with San Francisco +168. The point total is set at 50.5.

All odds are brought to us by FanDuel sportsbook.

Who will win?

Our contributors make their winners picks each week of the season. We mostly focus only on the straight-up winners. Some of the group, however, have also made picks against the spread and with the point total for each game. You can check out our picks, including the spread picks, in the widget below, provided to us by Tallysight.

Here are our Monday picks for Week 17.

Filed Under: Dolphins

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